Neisseria gonorrhoeae bacterial DNA load in the pharynges and saliva of men who have sex with men

EPF Chow; SN Tabrizi; S Phillips; D Lee; CS Bradshaw; MY Chen; CK Fairley

Journal article

Neisseria gonorrhoeae bacterial DNA load in the pharynges and saliva of men who have sex with men

EPF Chow, SN Tabrizi, S Phillips, D Lee, CS Bradshaw, MY Chen, CK Fairley

Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2016

DOI: 10.1128/JCM.01186-16

Abstract

Neisseria gonorrhoeae can be cultured in the saliva of individuals with pharyngeal gonorrhea. The aim of this study was to quantify the gonococcal bacterial DNA loads in the pharynges and saliva among men who have sex with men (MSM) with untreated pharyngeal gonorrhea. Untreated MSM who tested positive for pharyngeal gonorrhea by culture and returned for antibiotic treatment within 14 days at the Melbourne Sexual Health Centre between October 2014 and March 2015 were eligible for this study. The gonococcal bacterial DNA load was measured using real-time quantitative PCR. The median gonococcal bacterial DNA loads in the pharynges and saliva were calculated and compared to culture positivity u..

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University of Melbourne Researchers

Eric Chow Author

Catriona Bradshaw Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work, including the efforts of Eric P. F. Chow, was funded by Department of Health vertical bar National Health and Medical Research Council (NHMRC) (1091226). This work, including the efforts of Christopher K. Fairley, was funded by Department of Health vertical bar National Health and Medical Research Council (NHMRC) (568971).